“If we could do something that enhances the body’s immune system here on Earth, it would be a tremendous step forward in the fight against disease and cancer and other things” – John Glen


John, meet colostrum…colostrum, meet John

Colostrum vs Flu Vaccination

  • Colostrum contains high concentrations of specific immune modulating factors such as Immunoglobulins, Lactoferrin, Proline Rich Polypeptides, and Oligosaccharides.
  • Colostrum may help to restore the Thymus gland (a major contributor to human immunity) which dwindles in size and effectiveness with age.
  • Colostrum helps to make our natural disease fighting T-Cells react more efficiently and effectively when the body senses invading pathogens
  • Colostrum helps to combat cellular inflammation which is often a source of pain, allergies, asthma, skin disorders, and intestinal disorders
  • Colostrum accelerates collagen production which may speed up surface wound closure and has been observed to decrease some forms of dermatitis and psoriasis.
  1. Modulation of the immune system and the response against pathogens with bovine colostrum concentrates

NW Solomons

European Journal of Clinical Nutrition volume 56, pages S24–S28 (2002)


The growth, development and health conditions for children living under deprived conditions in developing countries are so adverse that immediate public health measures to reduce morbidity and improve nutrition are urgently needed. Preventing and shortening the course of diarrheal episodes, eliminating protozoal colonization, and balancing intestinal microflora would all contribute to these goals. The consumption by humans of part of the colostrum produced when a dairy animal gives birth is an established tradition in many traditional societies. Recent advances in food technology in industrial dairying allow for continuous availability of stabilized bovine colostrum concentrate, both natural and hyperimmunized against specific human pathogens. This is safe for the calves of the producers themselves, for laboratory animals, and generally for humans, with the caveat of the milk-allergic. Moreover, substantial amounts of orally ingested bovine colostrum concentrate survive their passage through the stomach to remain intact and active in the lower reaches of the bowel. Studies in animals, human volunteers and naturally infected humans have demonstrated a therapeutic efficacy of oral bovine colostrum with certain infections. Similarly, attempts to prevent gastrointestinal infections in animals, exposed volunteers and at-risk populations have met with limited success with specific pathogens. It is time to begin to assess the feasibility and potential effectiveness and efficiency of employing seasonal or chronic bovine colostrum feeding in populations of deprived infantile populations to reduce the rates of recurrent gastroenteritis and decrease immunostimulation to improve vitality and nutritional status in early life.

  1. Modulation of human humoral immune response through orally administered bovine colostrum

Fang He  Elina Tuomola  Heikki Arvilommi  Seppo Salminen

FEMS Immunology & Medical Microbiology, Volume 31, Issue 2, 1 August 2001, Pages 93–96,

Published: 01 August 2001  


Eighteen healthy volunteers were randomized into two treatment groups and consumed liquid prepackaged bovine colostrum whey and placebo for 7 days. On days 1, 3 and 5, an attenuated Salmonella typhi Ty21a oral vaccine was given to all subjects to mimic an enteropathogenic infection. The circulating antibody secreting cells and the expression of phagocytosis receptors of the subjects before and after oral immunization were measured with the ELISPOT assay and flow cytometry. All subjects responded well to the vaccine. No significant differences were observed in ELISPOT values for IgA, IgG, IgM, Fcγ and CR receptor expression on neutrophils and monocytes between the two groups. There was a trend towards greater increase in specific IgA among the subjects receiving their vaccine with bovine colostrum. These results suggest that bovine colostrum may possess some potential to enhance human special immune responses.

  1. Bovine milk antibodies for health

Hannu Korhonen (a1), P. Marnila (a1) and H. S. Gill (a2) Published online: 01 March 2007


The immunoglobulins of bovine colostrum provide the major antimicrobial protection against microbial infections and confer a passive immunity to the newborn calf until its own immune system matures. The concentration in colostrum of specific antibodies against pathogens can be raised by immunising cows with these pathogens or their antigens. Immune milk products are preparations made of such hyperimmune colostrum or antibodies enriched from it. These preparations can be used to give effective specific protection against different enteric diseases in calves and suckling pigs. Colostral immunoglobulin supplements designed for farm animals are commercially available in many countries. Also, some immune milk products containing specific antibodies against certain pathogens have been launched on the market. A number of clinical studies are currently in progress to evaluate the efficacy of immune milks in the prevention and treatment of various human infections, including those caused by antibiotic resistant bacteria. Bovine colostrum-based immune milk products have proven effective in prophylaxis against various infectious diseases in humans. Good results have been obtained with products targeted against rotavirus, Shigella flexneri, Escherichia coli, Clostridium difficile, Streptococcus mutans, Cryptosporidium parvum and Helicobacter pylori. Some successful attempts have been made to use immune milk in balancing gastrointestinal microbial flora. Immune milk products are promising examples of health-promoting functional foods, or nutraceuticals. This review summarises the recent progress in the development of these products and evaluates their potential as dietary supplements and in clinical nutrition.